The randomized crossover study involved 10 volunteers using scintigraphy with 81mKrypton ( 81mKr) gas during a breath-holding maneuver with closed mouth and in 3 nasally breathing tracheotomized patients by volumetric capnography and oximetry through sampling CO 2 and O 2 in the trachea and measuring the inspired volume with inductance plethysmography following NHF rates of 15, 30, and 45 l/min. The hypothesis of this study was that NHF in a dose-dependent manner can clear dead space of the upper airways from expired air and decrease rebreathing. Clearance of dead space has been suggested as being the key mechanism of respiratory support with NHF therapy. The coolest part of Clarke’s look has always been the energy glow of his mask and other components, and Kotobukiya has recreated that with LED lights in the statue’s helmet, backpack, and glove! There’s even a ball-joint in the hero’s neck so you can pose him to your liking.Recent studies show that nasal high flow (NHF) therapy can support ventilation in patients with acute or chronic respiratory disorders. The RIG suit flexes around Isaac as he lunges to one side in a battle stance with his trusty Plasma Cutter in hand. His gear is incredibly detailed with mechanical components, different textures of cloth, belts, pouches, seams, clothing creases, a fur-lined collar, and much, much more. Isaac wears his iconic Resource Integration Gear suit, complete with slitted facemask, with new alterations for the third game and its arctic setting. Tracking down the galactic menace to stop it once and for all, the former engineer turned hero Clarke stands triumphant after finishing off a Necromorph on the frigid Tau Volantis. Making his stunning ARTFX debut in his look from that game is the main player character Isaac Clarke! That game was followed up by a sequel in 2011, and Dead Space 3 is set to release in February 2013. The first game was released in 2008, introducing players to the horror/science-fiction setting where you must fight and dismember Necromorphs to stay alive. A Kotobukiya Japanese import! The next hit video game series to join Kotobukiya’s ranks of ARTFX statues is the epic Dead Space.
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